Propor SG
PROPOR SG sterilising grade filters feature a patented, microbially retentive polyethersulphone membrane for fast, reliable, and cost-effective sterile filtration of pharmaceutical fluids. The asymmetric pore structure and high voids volume of the PROPOR SG membrane allow high throughputs and exceptionally high flow rates compared with competitive PES and alternative membranes.
Low protein and preservative binding properties minimise product loss due to adsorption. PROPOR SG filters are optimised for pharmaceutical processing. They have low extractable levels and broad chemical compatibility across the full pH range, including organic solvents.
Technical Specifications
Materials of Construction
- Filtration Membrane: Polyethersulphone
- Upstream Support: Polyester
- Downstream Support: Polyester
Filter Cartridges
- Inner Support Core: Polypropylene
- Outer Protection Cage: Polypropylene
- End Caps: Nylon
- End Caps Insert: 316L Stainless Steel
- Standard o-rings/gaskets: Silicone
MURUS Disposable Filter Capsules
- Core: Polypropylene
- Sleeve: Polypropylene
- Standard o-rings/gaskets: Silicone
- Capsule Body: Polypropylene
- Capsules Vent Seals: Silicone
DEMICAP Filter Capsules
- Core: Polypropylene
- Sleeve: Polypropylene
- End Caps: Nylon
- Capsule Body: Nylon
- Capsules Vent Seals: Silicone
- Filling Bell: Polycarbonate
Syringe Filters
- Body: Polypropylene
Recommended Operating Conditions
- Filter Cartridges: Up to 70 °C (158 °F) continuous operating temperature and higher short-term temperatures during CIP to the following limits.
- MURUS Disposable Filter Capsules: Up to 25 °C (77 °F) @ 5.5 barg (79.7 psig); Up to 60 °C (140 °F) @ 2.8 barg (40.6 psig)
- DEMICAP Filter Capsules: Up to 40 °C (104 °F) at line pressures up to 5.0 barg (72 psig).
Parker Hannifin certify that this product complies with the European Council Pressure Equipment Directive (PED) 97/23/ EC Article 3, Paragraph 3 – Sound Engineering Practice (SEP). This product is intended for use with Group 1 & 2 Dangerous and Harmless Liquids and Group 2 Harmless Gases at the operating conditions stated in this document: In compliance with PED Article 3, Paragraph 3, SEP, this product does not bear the CE mark.
Effective Filtration Area (EFA)
- 10¨ (250 mm): 0.55 m² (5.92 ft²)
- K Size: 0.26 m² (2.79 ft²)
- A Size: 0.20 m² (2.15 ft²)
- B Size: 0.10 m² (1.07 ft²)
- E Size: 0.05 m² (0.53 ft²)
- Syringe ø50 mm: 14.50 cm² (2.25 in²)
Sterilization
PROPOR SG filter cartridges can be sanitised with hot water at up to 90 °C (194 °F) and are compatible with a wide range of chemicals. For detailed operational procedures and advice on cleaning and sterilisation, please contact the Technical Support Group through your usual Parker domnick hunter contact.
Food and Biological Safety
Materials conform to the relevant requirements of 21CFR Part 177 and current USP Plastics Class VI – 121 °C and ISO10993 equivalents.
Quality Standards
Pharmaceutical grade products are manufactured in accordance with cGMP, 100% flushed with pharmaceutical purified water and integrity tested prior to despatch. A sample of each lot is tested to demonstrate conformity to validated claims.
Gamma-Irradiation
PROPOR SG MURUS & DEMICAP disposable filters can be gamma-irradiated up to a maximum dosage of 40 kGy.
Features and Benefits
- Up to 3.5 times higher flow rates than competitive sterilising grade filters
- Fully validated and integrity testable membrane for assurance of sterility
- Low binding for minimal product loss
- MURUS and DEMICAP’s can be gamma-irradiated and autoclaved
