Propor LR
PROPOR LR filters have been specifically designed for high flow and effective removal of Ralstonia pickettii and other diminutive organisms. A number of studies have concluded that not all microorganisms are removed by 0.2 micron rated “sterilising” grade membranes under all conditions.
PROPOR LR filters use a 0.1 micron rated membrane, which can remove diminutive organisms, whilst maintaining flow rates typical of a 0.2 micron filtration system. Ralstonia pickettii is one organism that has frequently been shown to penetrate a 0.2 micron rated membrane and is a common contaminant in purified water systems.
PROPOR LR filters have been validated directly against the removal of Ralstonia pickettii.
Technical Specifications
Materials of Construction
- Filtration Membrane: Polyethersulphone
- Upstream Support: Polyester
- Downstream Support: Polyester
- Filter Cartridges
- Inner Support Core: Polypropylene
- Outer Protection Cage: Polypropylene
- End Caps: Nylon
- End Caps Insert: 316L Stainless Steel
- Standard o-rings/gaskets: Silicone
- MURUS Disposable Filter Capsules
- Core: Polypropylene
- Sleeve: Polypropylene
- Standard o-rings/gaskets: Silicone
- Capsule Body: Polypropylene
- Capsules Vent Seals: Silicone
- DEMICAP Filter Capsules
- Core: Polypropylene
- Sleeve: Polypropylene
- End Caps: Nylon
- Capsule Body: Nylon
- Capsules Vent Seals: Silicone
- Filling Bell: Polycarbonate
- Syringe Filters
- Body: Polypropylene
Recommended Operating Conditions
- Filter Cartridges: Up to 70 °C (158 °F) continuous operating temperature and higher short-term temperatures during CIP to the following limits:
- MURUS Disposable Filter Capsules: Up to 25 °C (77 °F) @ 5.5 barg (79.7 psig); Up to 60 °C (140 °F) @ 2.8 barg (40.6 psig). Parker Hannifin certify that this product complies with the European Council Pressure Equipment Directive (PED) 97/23/EC Article 3, Paragraph 3 – Sound Engineering Practice (SEP). This product is intended for use with Group 1 & 2 Dangerous and Harmless Liquids and Group 2 Harmless Gases at the operating conditions stated in this document. In compliance with PED Article 3, Paragraph 3, SEP, this product does not bear the CE mark.
- DEMICAP Filter Capsules: Up to 40 °C (104 °F) at line pressures up to 5.0 barg (72 psig).
Effective Filtration Area (EFA)
- 10¨ (250 mm): 0.55 m² (5.92 ft²)
- K Size: 0.26 m² (2.79 ft²)
- A Size: 0.20 m² (2.15 ft²)
- B Size: 0.10 m² (1.07 ft²)
- E Size: 0.05 m² (0.53 ft²)
- Syringe ø50 mm: 14.50 cm² (2.25 in²)
Sterilization
PROPOR LR filter cartridges can be sanitised with hot water at up to 90 °C (194 °F) and are compatible with a wide range of chemicals. For detailed operational procedures and advice on cleaning and sterilisation, please contact the Technical Support Group through your usual Parker domnick hunter contact.
Food and Biological Safety
Materials conform to the relevant requirements of 21CFR Part 177 and current USP Plastics Class VI – 121 °C and ISO10993 equivalents.
Quality Standards
Pharmaceutical grade products are manufactured in accordance with cGMP, 100% flushed with pharmaceutical purified water and integrity tested prior to despatch. A sample of each lot is tested to demonstrate conformity to validated claims.
Gamma-Irradiation
PROPOR LR MURUS & DEMICAP disposable filters can be gamma-irradiated up to a maximum dosage of 40 kGy.
Features and Benefits
- Fully correlated against Ralstonia pickettii and integrity testable
- Increases retention efficiency whilst maintaining existing 0.2 micron rated system size
- Up to 2.5 times higher flow rate than competitive 0.1 micron rated filters
- MURUS and DEMICAP’s can be gamma-irradiated and autoclaved
